Gastrointestinal Profiles

Calprotectin
Calprotectin belongs to a group of calcium-binding neutrophil-derived proteins. Calprotectin plays a regulatory role in the inflammatory process and it is released from neutrophils during activation and cell death. Calprotectin makes up about 60% of the cytosolic protein in neutrophils. Neutrophils are mobilized and activated in the gut, in response to: cell or tissue damage; increased permeability of the mucosa;and infectious processes. Thus, calprotectin is a reliable marker for the presence of infectious, inflammatory or malignant disease. Mechanistically, calprotectin has inhibitory effects on zinc dependent enzymes producing bactericidal and fungicidal properties with MICs comparable to those of many antibiotics.

Sample Report

1-Page Test Description